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In silico prediction software SIFT PolyPhen CADD and other
2019-05-16
In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com
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The exact incidences of amiodarone induced
2019-05-16
The exact incidences of amiodarone-induced hyperthyroidism and amiodarone-induced hypothyroidism currently remain unknown; however, the reported frequencies of amiodarone-induced hyperthyroidism and amiodarone-induced hypothyroidism vary widely from 0.8% to 37.8% [7–16] and from 1% to 32% [13,17–20]
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pamabrom The strategy seeks to reduce
2019-05-16
The 25×25 strategy seeks to reduce preventable mortality. This emphasis leads to the selection of the four disorders specified in the strategy (cardiovascular disease, diabetes, cancer, and chronic respiratory disease), which account for 87% of all deaths from NCDs (). However, when the burden of di
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d-biotin br zoonoses are responsible for
2019-05-16
13 zoonoses are responsible for a staggering 2·2 billion human illnesses and 2·3 million deaths per year, mostly in low-income and middle-income countries () where the correlation between rates of protein malnutrition and incidence of endemic zoonotic diseases is 99%. Veterinary medicine has an i
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An ERP in the ECG has been shown to be
2019-05-15
An ERP in the ECG has been shown to be familial [187–189]. ERP and ERS have been associated with variants in 7 genes. Consistent with the findings that IK-ATP activation can generate an ERP in canine ventricular wedge preparations, variants in KCNJ8 and ABCC9, responsible for the pore- forming and A
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Social determinants are the lived conditions ie social
2019-05-15
Social determinants are the lived conditions (ie, social and economic) that influence wellbeing, and environmental influences on behaviour are those assessed with the health behaviour theory. Stages of change models (ie, those that recognise health behaviour as a series of progressive steps leading
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bike With the publication of this month s
2019-05-15
With the publication of this month\'s issue, we mark \'s first birthday. I hope you will allow me to effuse for a moment in the manner of a new parent discovering the fascination of her offspring\'s everyday achievements… Since its conception in March, 2013, the infant has maintained a healthy int
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El ltimo espacio que Idalia visit fue
2019-05-15
El último espacio que Idalia visitó fue la sala de exposiciones del Centro Cultural Universitario Tlatelolco de la unam en 2012. La exposición “Pedro Valtierra. Mirada y testimonio”, permitió que este ícono de la obra de Valtierra adquiriera otro significado. A partir de esta retrospectiva se obtuvo
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br Introduction Multiple signal transduction pathways
2019-05-15
Introduction Multiple signal transduction pathways in normal and malignant congo red converge on Bcl-2 family proteins, which stand at the crossroads between cell survival and apoptosis. The seminal event in the intrinsic pathway of apoptosis is mitochondrial outer membrane permeabilization (MOMP
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CP-673451 The recently published global consensus recommenda
2019-05-15
The recently published global consensus recommendations on prevention and management of rickets advocate for the eradication of rickets and osteomalacia through implementation of national supplementation and food fortification programmes containing vitamin D, calcium, or both. On the basis of high-q
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br Sensors for HF monitoring can
2019-05-15
Sensors for HF monitoring can be classified according to the technical instrumentation. Table 2 summarizes the sensors that have been used or proposed to monitor the events of HF. The paced QRS enables the determination of the QT duration. In addition, the QRS width, measured as the ventricular de
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cyclin dependent kinases br de Hern n Lara Zavala se
2019-05-15
de Hernán Lara Zavala se suma al acervo literario de novelas históricas de México. En los albores del México independiente, la novela histórica representó una vía de exploración y defini-ción del “ser nacional”. A casi dos siglos de distancia la novela histórica ocupa un lugar central en la produc
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Ante la falta de un ambiente estimulante
2019-05-15
Ante la falta de un ambiente estimulante para la producción de un pensamiento crítico y una conciencia social, Pablo Molinet (1975) escribe: “Quizá nuestra época nos dejó hablando solos” (93). No es de extrañar: luego de 1968, las concentraciones de jóvenes fueron vistas como un peligro y se dispuso
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d-biotin En efecto lecturas atentas de estos textos sabr n l
2019-05-15
En efecto, lecturas atentas de estos textos sabrán localizar “lo político” de su empeño signado, más allá de referirse o hacer mención d-biotin políticas específicas, encontradas al paso en los lugares que visitan y recorren, o de hablar sobre los personajes políticos que conocen; más allá, pues, de
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An interesting finding in the study of Ngabo and
2019-05-14
An interesting finding in the study of Ngabo and colleagues was that, after a huge drop in the number of admittances to hospital for rotavirus in 2013, there was no further fall the next year. As the researchers discuss, this finding might herald the beginning of a biennial pattern of rotavirus acti
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