• Our finding that the ATRX DAXX H complex

  2021-06-01

  

  Our finding that the ATRX-DAXX-H3.3 complex promotes a form of HR is likely to have important implications for our understanding of the ALT recombination process that takes place at telomeres. We were surprised to observe that ATRX promotes a form of HR, since loss of the ATRX-DAXX-H3.3 complex is n

• br Introduction Pattern separation is the ability to

  2021-06-01

  

  Introduction Pattern separation is the ability to make distinct representations from highly overlapping information, a process which is important for memory encoding (Clelland et al., 2009). For correct pattern separation, old information needs to be retrieved and compared to new information. If

• Our results suggest that formation of DDR b clusters may

  2021-06-01

  

  Our results suggest that formation of DDR1b clusters may be important for and precede receptor phosphorylation. Indeed, while DDR1b clustering was readily detected (by YFP signal) 30 min after collagen administration, phosphorylated DDR1 species at Y513 (present in the IJXM) were evident after 4 h o

• One of the most frequent

  2021-06-01

  

  One of the most frequent gene alterations in MM is methylation of the p15 and p16 genes in the 5′ upstream region. P15 and p16 proteins are PD 123319 ditrifluoroacetate regulators involved in the inhibition of transition from G1 to S phase. Frequencies of p15 or p16 gene methylation up to 32% and

• The isolation of a proteinaceous putative inhibitor of cyste

  2021-06-01

  

  The isolation of a proteinaceous putative inhibitor of cysteine proteases from the extracts of Y. enterocolitica and E. coli was performed by affinity chromatography on immobilized and inactivated papain (Fig. 7A). Instead of the column variant of this technique (Tsushima et al., 1992), we used a ba

• br Materials and methods br Results br Discussion In this

  2021-06-01

  

  Materials and methods Results Discussion In this study, we developed a new CysLT1 and CysLT2 receptors-mediated endothelin receptor guinea pig model for screening both CysLT2 receptor and CysLT1/2 receptor antagonists. Unlike human CysLT2 receptors, which are equally stimulated by both LTC

• Higher versus lower order skills

  2021-06-01

  

  Higher versus lower order skills can also be understood in the context of the CPA exam. The CPA exam tests four broad topics (FAR, AUD, BEC, REG) using three different testing modes: multiple-choice, task-based simulations and written communications. Combined, the three testing modes place more emph

• Cubic equations of state CEoS are particularly popular

  2021-06-01

  

  Cubic equations of state (CEoS) are particularly popular due to their simplicity and relatively good accuracy in predicting vapour-liquid equilibrium and liquid-liquid equilibrium for small, non-polar, non-associating molecules, such as light hydrocarbons. CEoS can match the phase boundaries (L/LL a

• Oxaliplatin In this context our observation that

  2021-06-01

  

  In this context, our observation that the Oxaliplatin predictor of positive QFN-CMV responses is background CMV seropositivity was not unexpected. Older age, despite well-known effects of CMV memory inflation did not appear to independently impact QFN-CMV responses in our study. The inter-play betw

• The MOF system described by Farha and

  2021-05-31

  

  The MOF system described by Farha and coworkers combines rational design of the support and good experimental results regarding activity and stability. However, a further increase in the speed of enzyme loading into the MOF and a decrease in leaching are still required. How can the design rules prop

• Introduction CYP is a superfamily of heme containing monooxy

  2021-05-31

  

  Introduction CYP450 is a superfamily of heme-containing monooxygenases, many of which are expressed in the liver, and they are significant phase-I pak1 inhibitor in drug metabolism and detoxification. There are three subfamilies (CYP1, CYP2 and CYP3) that are mainly involved in the metabolism of d

• br Introduction The Epstein Barr virus induced gene EBI

  2021-05-31

  

  Introduction The Epstein–Barr virus induced gene 2 (EBI2 also known as GPR183) is a G protein-coupled seven-transmembrane (7TM) receptor that is predominantly expressed in B and T cells [1,2]. It regulates the trafficking of Zanamivir within lymphoid tissues and is highly important for the genera

• br Experimental br Acknowledgments The work

  2021-05-31

  

  Experimental Acknowledgments The work was supported in part by the National Research and Development Plan (2017YFD0200506), the National Natural Science Foundation of China (21472062 and 31701820), 111 Project B17019, and excellent doctoral dissertation cultivation Grant from Central China Nor

• In the present study we implemented the

  2021-05-31

  

  In the present study, we implemented the dendritic RCA-induced formation of amplifying DNAzyme catalytic labels strategy for sensitive and accurate assay of MTase activity and the detection of DNA methylation. In comparison with the traditional RCA process, the proposed strategy achieved high amplif

• Proteolysis by CPs is crucially important for

  2021-05-31

  

  Proteolysis by CPs is crucially important for cereal seed development and germination. However, these enzymes must be tightly controlled. Pre-harvest sprouting is a phenomenon in which the control of CPs is disrupted. This disruption manifests in the premature synthesis and activation of CPs, leadin

14700 records 576/980 page Previous Next First page 上5页 576577578579580 下5页 Last page