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If the effects described here
2021-03-11
If the effects described here are present in catalysis, their empirical confirmation poses many challenges. Cat state correlations are fragile outside an environment especially suited for their preservation. As present day observational techniques whether in vivo or in vitro were not designed bearin
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Tropical theileriosis is caused by the apicomplexan parasite
2021-03-11
Tropical theileriosis is caused by the apicomplexan parasite Theileria annulata which is transmitted by a tick vector from the genus Hyalomma in cattle (Echebli et al., 2014, Li et al., 2014). Theileria parasites invade the leukocytes by sporozoites secreted from the vector, schizonts mature into me
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Upon assembly of HLA tetramers loaded
2021-03-11
Upon assembly of HLA tetramers loaded with either of the two peptide versions, we could query the T cell repertoires of RA subjects and healthy individuals for the presence of cognate T NP118809 receptor recognizing the respective peptide-HLA complexes. We found no significant difference in frequenc
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The significance of the difference in the DDR
2021-03-11
The significance of the difference in the DDR2 binding specificity towards fibrillar and non-fibrillar collagens is not understood, but may imply differences in biological responses when chondrocytes bind to different collagens in the growth plate. Investigations by Labrador et al. (2001) have shown
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br Acknowledgments The authors acknowledge funding
2021-03-11
Acknowledgments The authors acknowledge funding from the National Key Research and Development Program of China (2016YFA0502900) and the National Science Foundation of China (31570188). Compartment Size Regulation Regulation of compartment size is one of the most fundamental issues in biology
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Accordingly we prepared three compounds and as shown in Cond
2021-03-11
Accordingly, we prepared three compounds (, , and ) as shown in . Condensation of commercially available Mocetinostat synthesis with glycine methyl ester gave amide . A Friedel–Crafts reaction between compound and 4-methyl valeryl chloride in the presence of aluminum chloride mainly produced und
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br Results and discussion br
2021-03-11
Results and discussion Conclusion Based on the structure of ThDP, in this study, a series of novel ThDP analogs 6a-6g and 8a-8g were designed by optimizing triazole-benzene linker and modifying the substituent group of triazole ring. Then they were synthesized as potential inhibitors of Cy-PDH
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Several reports by us and others have highlighted that dimer
2021-03-10
Several reports by us and others have highlighted that dimerization or oligomerization of DDR1 ECD and DDR2 ECD enhances their binding to triple-helical collagen.18, 19, 22, 28, 29, 30, 31 The ECD of DDRs consists of a discoidin domain and a stalk region. It has been reported that independent DASA-5
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Resiquimod HvPap a member of the cathepsin F like family
2021-03-10
HvPap-1, a member of the cathepsin F-like family, was identified in germinating barley seeds (Sreenivasulu et al., 2008). This enzyme participates in the mobilization of stored proteins (mainly hordeins) during the last phase of grain germination, and its activity is modulated by a propeptide or/and
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br Acknowledgments The authors thank Elisabete Lepera
2021-03-10
Acknowledgments The authors thank Elisabete Lepera and Rosana Silva for technical support. The study was supported by FAPESP, CNPq and PADC/FCF-UNESP. T.T. Miguel was the recipient of a FAPESP (Proc. 05/05171-1) and R.L. Nunes-de-Souza of a CNPq (Proc. 303580/2009-7) fellowship. Introduction
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Assessment of the activity of
2021-03-10
Assessment of the activity of native and denatured TAT-CPG2 after penetration suggests that TAT-CPG2 has been successfully delivered into the cells, and the transduced enzyme is functional inside the cells. The enzyme activity of both native and denatured TAT-fusion proteins in the cultured HepG2 GW
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Park et al expanded their own
2021-03-10
Park et al. [34] expanded their own model as hydrogen- bonding lattice fluid EOS (NLF-HB) [35] for calculating the activity coefficients of aqueous amino rifadin solution. Further, Pazuki et al. [36] extended the perturbed hard chain theory which has been proposed by Beret and Prausnitz [37] for mod
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Bearing in mind that temperamental traits are genetically de
2021-03-10
Bearing in mind that temperamental traits are genetically determined, in the present study we have chosen to investigate COMT and OPRM1 gene polymorphisms related to stimulation of the nervous system, which is extremely important in combat sports. The μ-opioid receptor gene OPRM1 is located on the
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All of these experiments in GM matter injury
2021-03-10
All of these experiments in GM matter injury models have identified an array of signaling mechanisms that are potentially important. First, Kim et al. proposed that CK2 acts as a negative modulator of NADPH oxidase [55]. Then Blanquet et al. [50] found that increased CK2 correlated with inhibition o
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The evaluation of internal exposure in workers with
2021-03-10
The evaluation of internal exposure in workers with omethoate is challenging. Unfortunately, OPs are metabolized and excreted quickly in the urine usually within 24–48 h of exposure, and the variation in metabolic rates exists. Many factors influence daily urinary output, such as salt intake, urea a
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