Archives
- 2018-07
- 2019-04
- 2019-05
- 2019-06
- 2019-07
- 2019-08
- 2019-09
- 2019-10
- 2019-11
- 2019-12
- 2020-01
- 2020-02
- 2020-03
- 2020-04
- 2020-05
- 2020-06
- 2020-07
- 2020-08
- 2020-09
- 2020-10
- 2020-11
- 2020-12
- 2021-01
- 2021-02
- 2021-03
- 2021-04
- 2021-05
- 2021-06
- 2021-07
- 2021-08
- 2021-09
- 2021-10
- 2021-11
- 2021-12
- 2022-01
- 2022-02
- 2022-03
- 2022-04
- 2022-05
- 2022-06
- 2022-07
- 2022-08
- 2022-09
- 2022-10
- 2022-11
- 2022-12
- 2023-01
- 2023-02
- 2023-03
- 2023-04
- 2023-05
- 2023-06
- 2023-08
- 2023-09
- 2023-10
- 2023-11
- 2023-12
- 2024-01
- 2024-02
- 2024-03
- 2024-04
- 2024-05
- 2024-06
- 2024-07
- 2024-08
- 2024-09
-
br Conclusions br Introduction In the
2023-01-30
Conclusions Introduction In the modern life of humans, Oseltamivir phosphate are widely prescribed for therapy against bacterial diseases to prevent the onset of bacterial infections during a viral disease (Goossens et al., 2005; Van Boeckel et al., 2014). They have been massively administere
-
Sorafenib was the first small RTK inhibitor
2023-01-30
Sorafenib was the first small RTK inhibitor drug to be developed and was initially approved against renal cell carcinoma, then against hepatocellular carcinoma (HCC) and more recently for differentiated thyroid treatment [111]. Sunitinib soon followed, being approved for gastrointestinal stromal tum
-
Discussion The present experiments follow up and are complet
2023-01-30
Discussion The present experiments follow-up and are completely consistent with our prior findings [26] that blood Aβ is subject to peripheral clearance by a major pathway for circulating pathogens in primates, immune adherence [30,31]. CR1-mediated erythrocyte immune adherence, as well as CR1-medi
-
AHR is essential for IL production by T
2023-01-30
AHR is essential for IL-22 production by T Z-VEID-FMK australia and ILC3s [83]. Coexpression of AHR and RORγt by retroviral transduction in a thymoma cell line, EL4, synergistically upregulates IL-22 expression [48]. The cooperativity between AHR and RORγt has also been observed in primary T cells
-
We have previously shown that the antinociceptive effect of
2023-01-30
We have previously shown that the antinociceptive effect of tramadol, an analgesic that, like paracetamol is able to increase serotonin levels within CNS, is potentiated or antagonized respectively by a 5-HT1A/B nonspecific bestatin receptor blockade or activation (Rojas-Corrales et al., 2000). More
-
In young animals the HT A receptor antagonist
2023-01-30
In young animals, the 5-HT2A hedgehog signaling antagonist ketanserin, at relatively low concentrations, shifted 5-HT concentration-response curves rightward, suggesting a role for 5-HT2A receptors in mediating 5-HT-induced contractions of the ureter. The slopes of the ketanserin Schild plots for t
-
Serum soluble sCD is a shedding
2023-01-30
Serum soluble sCD21 is a shedding product from the ectodomain of membrane CD21 after B cell activation (Masilamani et al., 2003, Masilamani et al., 2004a, Masilamani et al., 2004b, Grottenthaler et al., 2006, Hoefer et al., 2008), which resembles the ligand-binding capacity of intact CD21 (Wu et al.
-
br Materials and methods br Results br Discussions Our
2023-01-30
Materials and methods Results Discussions Our results indicated that autophagy was suppressed in GECs under HAGG treatment, through Akt/mTOR-dependent pathways. Previous reports provided clues for the linkages between ICs and endothelial cell autophagy. Fujii and colleagues reported that se
-
br Discussion br Acknowledgments Writing of this review and
2023-01-30
Discussion Acknowledgments Writing of this review and collection of data from our laboratories that are presented were supported by a grant from the Belgian Science Policy (BELSPO) SSTC Interuniversity Attraction Poles Plastoscine P7/17 to AVDL and JB, multiple grants from the Fund for Scienti
-
Phenolic compounds show reciprocal relationship with colonic
2023-01-30
Phenolic compounds show reciprocal relationship with colonic microflora. Phenolic compounds are able to improve colonic health and modulate microbiota diversity with prebiotic and antimicrobial functions, while colonic bacterial enzymes catalyze deconjugation, dehydroxylation, and convert phenolic c
-
Various compounds have been designed to inhibit aldose reduc
2023-01-29
Various compounds have been designed to inhibit aldose reductase (AR) [12]. These compounds can be classified into two main categories, the first category comprises those containing a carboxylic UNC 0642 moiety, for example, 3-thiazolidineacetic acid derivative, which has been reported to be a poten
-
Flavonoids protein interactions studies play a
2023-01-29
Flavonoids-protein interactions studies play a substantial part in the hunt for novel molecules which are to interact with a selected disease-relevant target [35]. The mode of potential interaction gives information about the flavonoid effectiveness and selectivity. Lately, possible target molecules
-
KH 7 Until now there are no report regarding
2023-01-29
Until now, there are no report regarding the relationship of CD21 and MG. In the present study, we aimed to characterize the AchR specified KH 7 and investigated the role of CD21 in immunopathogenesis of MG. We utilized the Allophycocyanin (APC)-conjugated AchR to measure the frequencies of AchR spe
-
It has been reported that leukotrienes and their receptors e
2023-01-29
It has been reported that leukotrienes and their receptors, e.g. the cysteinyl leukotriene receptor 1 (CysLT1) may promote cetylpyridinium injury (Ding et al., 2007) and that increased 5-LOX expression and activity lead to production of brain-toxic molecules (Khan et al., 2010). However, differentia
-
However although in vitro studies in heterologous systems
2023-01-29
However, although in vitro studies in heterologous systems have provided very important indications of potential novel pharmacology, the studies with endogenous receptors in native tissues are essential to provide evidence for GPCR heteromerization in vivo and to confirm its physiological relevance.
14176 records 251/946 page Previous Next First page 上5页 251252253254255 下5页 Last page