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V ATPase is a complex enzyme that is composed of
2023-10-07
V-ATPase is a complex enzyme that is composed of several subunits, which are assembled into two domains: trans-membrane (V0) and cytosolic (V1) domains [3,5]. Epididymal epithelial TUG-770 of rats has been reported to contain V-ATPase which is distributed at the apical pole of the narrow and clear c
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br Materials and methods br Results br Discussion Fluoride c
2023-10-07
Materials and methods Results Discussion Fluoride can readily penetrate cellular membranes and seriously damage the structure and physiological function of cells (Zhou et al., 2015). Several studies have shown that excessive fluoride can decrease the viability of cells and that the growth o
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Previous research showed that combination of chitosan
2023-10-07
Previous research showed that combination of chitosan and Dinaciclib nanocrystals (CNCs) can produce coating films with superior properties (Naseri, Mathew, Girandon, Fröhlich, & Oksman, 2015). CNCs are crystalline nanometer sized rod-like particles. It has been demonstrated that antimicrobial activ
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Intracellular Signaling Cascades From ligand sensitization
2023-10-07
Intracellular Signaling Cascades. From ligand sensitization to translation of genes, all cellular processes are dependent on the intracellular levels and activity of partners involved in the signaling pathway. These signaling events lead to critical post-translational modifications including phospho
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cudc mg An AXL decoy receptor with enhanced GAS
2023-10-03
An AXL decoy receptor with enhanced GAS6-binding properties, MYD1, was engineered as a therapeutic tool to disrupt GAS6/AXL signaling in vivo (Kariolis et al., 2014). MYD1 was shown to block metastasis of human ovarian cancer cudc mg and a murine breast cancer cell line in grafting assays in mice. T
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Fig summarizes the oxidative metabolism of arachidonic
2023-10-03
Fig. 1 summarizes the oxidative metabolism of arachidonic NSC 207895 by lipoxygenases cyclooxygenases and cytochrome P450. Lipoxygenases in humans are expressed in a tissue-specific fashion: 5-LOX is mainly expressed in leukocytes, 12-LOX in platelets, and 15-LOX-1 in reticulocytes, eosinophils, a
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To further investigate the role
2023-10-03
To further investigate the role of cholesterol in the Rh2-induced cytotoxicity, we then focused on the U937 cell line, which is cholesterol auxotroph and considered as a valuable model to study the importance of cholesterol in membrane structure and function (Billheimer et al., 1987), and used the e
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In conclusion there are only a
2023-10-01
In conclusion, there are only a few experimental reports evaluating the influence of g15 mg on allergy. With the exception of studies using macrolides, most point to their harmful effect on the severity of this disease. Future studies will be crucial to define the impact of antibiotic use on allerg
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br Methodology br Antibiotics in lakes br
2023-10-01
Methodology Antibiotics in lakes Antibiotic resistance genes in lakes Perspectives of study on JNJ 5207852 dihydrochloride and ARGs in lakes Conclusion This paper systematically reviewed the distribution of antibiotics and ARGs in global lakes. A total of 57 antibiotics reported at le
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br Conclusions br Acknowledgments br Introduction The surfac
2023-10-01
Conclusions Acknowledgments Introduction The surface water bodies are affected by effluents containing pollutants from wastewater treatment plants, storm water overflows and run-off from non-point sources like agricultural land and urban city surfaces. This relates to land-based sources occ
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br Introduction Androgens have been shown to regulate severa
2023-10-01
Introduction Androgens have been shown to regulate several neural functions ranging from reproduction to mood and cognitive abilities. This property starts as early as the perinatal period, which is characterized by prenatal and postnatal surges of gonadal testosterone, and continues through pube
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However in recent years advanced experiments and
2023-10-01
However, in recent years advanced experiments and findings are emerging to give us more detailed information on Aβ-membrane interactions. Several reviews have provided background on the fibrillation of Aβ and the Aβ-membrane interactions [[18], [19], [20], [21], [22]]. In this review, we mainly focu
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br Acknowledgments br Introduction Within the classical secr
2023-10-01
Acknowledgments Introduction Within the classical secretory pathway, transmembrane and soluble cargos travel via the endoplasmic reticulum (ER) and Golgi apparatus en route to their final destinations [1]. However, at a post-Golgi level, trafficking routes can diverge. In this context, the tra
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Adenosine receptors activate a number of signalling pathways
2023-10-01
Adenosine receptors activate a number of signalling pathways involved in tissue survival including several mitogen-activated protein kinases (Fredholm et al., 2001). The common feature of all adenosine receptors is the positive coupling to ERK1/2, whilst A2B and A3 receptors can also activate the st
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5-Methoxy-UTP synthesis After infection with Salmonella thos
2023-09-28
After infection with Salmonella those bacteria that are not targeted by autophagy of the complete Salmonella-containing phagosome (see above) but are living freely in the cytosol can be eliminated by xenophagy, that is direct targeting of the ‘naked’ bacteria to the autophagic pathway. The type III
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