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However days after he completed
2019-06-10

However, 10 days after he completed the last chemotherapy round with etoposide, the patient again visited our emergency department manifesting a fever. Lab data reported leukopenia, anemia, and elevated LDH (leukocyte:3600/μL, hemoglobin:10.9 g/dL, platelet:168 × 103/μL, and LDH:498 U/L). Thereafter
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Elacridar Initial radiographs demonstrated an aggressive les
2019-06-10

Initial radiographs demonstrated an aggressive lesion in the medial condyle of the distal right femur (Figs. 1A and B). CT obtained to characterize matrix showed an aggressive lesion with a focus of dense linear matrix (Fig. 2) with intervening lucent areas. The lesion was felt to be indeterminate a
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In this study we applied a more
2019-06-10

In this study, we applied a more general approach along these lines, which has previously been used only in few reports in the literature [8]. Based on a prospective BC database including all newly diagnosed BC cases at a large Swiss breast center over a 20-year period, we aimed to give a comprehens
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br Outstanding questions br Conflict of interest br
2019-06-10

Outstanding questions Conflict of interest Acknowledgments This work was supported by the Dutch Cancer SocietyUL2015-7599 KWF (EZ). Platelets and cancer metastasis Blood platelets play a primary role in wound healing and hemostasis. Since the first observation made (on himself) by the s
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Currently we are unable to fully
2019-06-06

Currently, we are unable to fully understand the nrf2 keap1 and distribution of the AT arising around the apex of the triangle of Koch. Koyama et al. closely studied the spatial and topographic variation in the distribution of this type of AT around the His-bundle [17]. As demonstrated in the presen
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The lack of a single identified correlate of protection for
2019-06-06

The lack of a single identified correlate of protection for LAIV should not deter future immunogenicity studies in resource-limited settings, especially using systems vaccinology approaches designed to dissect the complex interplay of innate and adaptive pathways following vaccination. John C Victor
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Introduction Bone is a very dynamic tissue resulting
2019-06-06

Introduction Bone is a very dynamic tissue resulting from coordinated phases of formation and resorption called bone remodelling. Additional to its role in phosphocalcic homoeostasis, bone remodelling process is necessary for bone growth, for renewal of cellular and extracellular matrix components
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br Conclusion br Conflict of interest
2019-06-06

Conclusion Conflict of interest Introduction Dermatofibrosarcoma protuberans (DFSP) is a rare soft-tissue neoplasm that was first identified by Taylor, RW in 1890. It was then described in 1924 by Darier, J and Ferrand, M as a progressive recurrent dermatofibroma, and was later termed DFSP
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Introduction The heart beat provides
2019-06-06

Introduction The heart beat provides the mechanical force for the pumping of oxygenated blood to, and deoxygenated blood away from, the peripheral tissues [1]. This depends critically on the orderly activation and recovery of electrical excitation through the myocardium. Disruptions of this can lea
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br Conflict of interest br Acknowledgments
2019-06-06

Conflict of interest Acknowledgments Background of basic genetics The human genome contains approximately 3 billion nucleotide order eicosapentaenoic acid pairs contained in 23 chromosome pairs. Each chromosome contains hundreds to thousands of genes and the estimated 30,000 genes in the h
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Thomas Hoeksema por su parte explica la paradoja
2019-06-06

Thomas Hoeksema, por su parte, explica la paradoja del título del siguiente modo: “la destrucción (fuego) está moderada por la estabilidad y la armonía (reposo). La relación entre estas dos fuerzas es multidimensional y dialéctica”. Para Hoeksema, el segundo volumen poético de Pacheco se debe entend
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The Cl HCO anion exchanger AE
2019-06-06

The Cl−/HCO3− anion exchanger 2 (AE2) is found on cholangiocytes and regulates intracellular pH homeostasis and stimulates bicarbonate secretion. Previous reports have revealed that PBC patients show decreased biliary AE2 expression, and researchers hypothesized that this decrease in AE2 RPC1063 ma
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Ulises criollo pertenecer a a lo
2019-06-05

Ulises criollo pertenecería fak inhibitor lo que en inglés se cataloga como nonfiction prose. Al escribirlo la principal intención de Vasconcelos no fue la de narrar en el sentido ficcional (imaginativo, desinteresado, novelesco) sino interpretar, sentar una comprensión de su época y de su país a pa
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Complete surgical resection of the tumor at the time of
2019-06-05

Complete surgical resection of the tumor at the time of diagnosis is essential towards effective management of PPB. Unfortunately, a large cohort of patients present with an advance stage of disease where the tumor has grown to such an extent to invade surrounding vital structures, hindering the com
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Case report A previously healthy year old man was referred
2019-06-01

Case report A previously healthy 37-year-old man was referred to our hospital in September 2015 with fever (between 37 and 38°C) for 10 days and general malaise. There was no history of recent travel, and the patient had no animals in his home. There were no remarkable features in the heart, lungs,
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