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Leptin synthesized in adipocytes is
2019-06-29

Leptin, synthesized in adipocytes, is a regulator of fat metabolism and reproduction [7]. The levels of leptin correlate with body fat mass and show a wide variation in individuals. In the bone marrow microenvironment, the leptin secreting adipocytes occupy a significant part [8]. Leptin stimulates
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The number of residents in London who were
2019-06-29

The number of residents in London who were originally from the 21 endemic countries in Central and South America was calculated from the 2011 UK National Census and was stratified by borough. We did not include undocumented migrants and individuals born to mothers from endemic Latin American countri
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We did a qualitative analysis to estimate the potential
2019-06-29

We did a qualitative analysis to estimate the potential risk of Zika VX-950 introduction into the country. We used the circlize statistical package for R software to visualise incoming traffic (logarithm of relative passenger volume) to Pakistani airports from countries characterised as Zika-virus-i
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br Material and methods br Results br Discussion The
2019-06-29

Material and methods Results Discussion The present study provides clinical, molecular, and in vitro electro-physiological evidence that a rare SNP (KCNE1-D85N) can act as a genetic modifier in LQTS. In general, SNPs are thought to be non-pathological, but some have been reported to modify
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Evidentemente la institucionalidad junto a la paralela ret r
2019-06-28

Evidentemente, la institucionalidad, junto AG 1879 la paralela retórica de reconciliación, no fue nunca suficiente para hacer de la reinserción del combatiente campesino un proceso fluido en esa sociedad pacificada. Fue, al contrario, un proceso dispar y enredado, lleno de ausencias y silencios. Den
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M s adelante del fragmento
2019-06-28

Más adelante del fragmento arriba citado de Memórias, hallamos otro en el que se aborda la cuestión de la insensibilidad. Graciliano la juzga extraña al igual que extraordinaria le parece la desaparición de los deseos sexuales: afirma que todos los sentidos desfallecían. Si son los sentidos los que
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In most patients with MCL multi organ
2019-06-28

In most patients with MCL, multi-organ involvement with organ damage is seen [2–5,10]. In most cases, the BM is the primary site of disease evolution [13]. However, only a smaller subset of patients with MCL present with circulating MC, and only very few cases present with rapidly increasing numbers
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br Introduction Acute myeloid leukemia AML remains a hematol
2019-06-28

Introduction Acute myeloid leukemia (AML) remains a hematologic malignancy with poor outcome and a high risk for relapse believed to be caused by the survival of leukemic stem cells (LSCs), which are responsible for disease repopulation following treatment [1]. This important implication of LSCs
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Two months from the initiation of dasatinib abnormal FDG upt
2019-06-28

Two months from the initiation of dasatinib, abnormal FDG uptake of the left femur tumor had disappeared. Examination of peripheral blood and the bone marrow examination showed that a complete cytogenetic response was achieved and a ratio of BCR-ABL to ABL on the international scale was 0.21%. Her d
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In most patients with MCL multi organ involvement
2019-06-28

In most patients with MCL, multi-organ involvement with organ damage is seen [2–5,10]. In most cases, the BM is the primary site of disease evolution [13]. However, only a smaller subset of patients with MCL present with circulating MC, and only very few cases present with rapidly increasing numbers
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br Results and discussion In this
2019-06-28

Results and discussion In this study, the np9 and gag mRNA expression was established for 25 patients with CLL (Fig. 1). We found that the transcriptional activity of HERV-K np9 gene in CLL patients was higher than in PBMCs from healthy donors. The results revealed that 18 out of 25 CLL patients
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While this report demonstrates that CMA with SNP arrays
2019-06-28

While this report demonstrates that CMA with SNP arrays is useful for the analysis of genomic imbalances in the peripheral blood of patients with suspected MDS, this technique is not readily available at many medical centers and many institutions perform fluorescence in situ hybridization to detect
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Chronic immunosuppression has been reported to be
2019-06-28

Chronic immunosuppression has been reported to be linked with PEL [11]. Several patients with concomitant PEL and HIV infection were reported. Thus, a small portion of the elderly with immunosuppressive conditions may have a tendency to develop MALT lymphoma. Our elderly patient had no HIV infection
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By showing the great variability in surgical
2019-06-28

By showing the great variability in surgical outcomes across LMICs, Uribe-Leitz and colleagues have shared with the world instructive knowledge that aids our ongoing advocacy efforts to promote quality in surgical care in resource-limited settings. Ultimately, for destitute sick and injured patients
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The overall MSTS score in our study was The
2019-06-28

The overall MSTS score in our study was 97.3%. The MSTS score after curettage treatment was 99%, better than that in previous studies, which ranged from 90% to 93%. Two cohort studies showed higher MSTS scores for patients who underwent intralesional curettage than those who underwent wide resection
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